Native Bacillus fastidiosus Uricase
| Cat# | DIA-173 |
| Source | Bacillus fastidiosus |
| Description | The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 → allantoin + CO2 |
| Form | Freeze dried powder |
| Activity | 15 U/mg |
| CAS No. | 9002-12-4 |
| Unit Definition | One unit will oxidize one micromole of uric acid at pH8.5 at 25°C. |
| Storage | -20°C |
| Synonyms | urate oxidase; uric acid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II; UO |
| Enzyme Commission Number | EC 1.7.3.3 |
| pH Stability | 5.5-10.0 (25°C for 20 hrs) |
| Optimum pH | 7 |
| Optimum temperature | 37°C |
| Thermal stability | Stable at 50°C and below (pH 7.0, 15 mins) |
| Inhibitors | Ag+, Hg2+ |
| Contaminants | Cholesterol oxidase < 0.005%; Catalase < 1%; Glucose oxidase < 0.005% |
| Abbr | UO (Bacillus fastidiosus) |
| Alias | UO; uricase |
| Product Overview | Urate:oxygen oxidoreductase produced in microorganism has a molecular mass of approximately 34 kDa. |
| Appearance | White to off-white powder |
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