Products
Comprehensive Portfolio of Diagnostic Enzymes and Reagents
At Creative Enzymes, we provide a complete portfolio of diagnostic-grade enzymes, kits, and related reagents designed for in-vitro diagnostics (IVD), point-of-care testing (POCT), and research applications. Each enzyme is developed, purified, and validated to meet the highest standards of clinical diagnostics, ensuring exceptional purity, reproducibility, and functional stability under assay conditions.
Our products support a broad range of diagnostic assays—from clinical biochemistry and metabolic disorders to molecular diagnostics and biosensor development—helping diagnostic companies accelerate assay design, reduce validation cycles, and ensure consistent lot-to-lot performance.
Our enzymes are classified by their diagnostic application fields, enabling customers to easily match reagents with specific testing needs.
Enzymes designed for serum and plasma analysis support routine biochemical assays such as creatinine, triglyceride, cholesterol, and glucose measurement. Each enzyme is optimized for high catalytic activity and minimal matrix interference in blood-derived samples.
Creative Enzymes supplies enzyme systems that form the foundation of colorimetric, chemiluminescent, and fluorometric diagnostic assays, ensuring precise quantification of clinical biomarkers in automated analyzers and POCT platforms.
We offer glucose oxidase, glucose dehydrogenase, and hexokinase for accurate blood glucose monitoring. Each enzyme exhibits high substrate specificity, low oxygen dependency, and superior thermostability, supporting both strip-based and liquid assays.
Diagnostic enzymes such as creatininase, urease, amylase, and lipase are validated for renal and pancreatic panels. These enzymes deliver linearity across physiological ranges and consistent reaction kinetics for quantitative diagnostic accuracy.
Enzymes like glutamate dehydrogenase (GLDH), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) serve as key biomarkers for hepatic function testing, produced under strict quality control to meet IFCC traceability.
For biosensor developers, Creative Enzymes provides immobilizable enzymes with enhanced film adhesion, cofactor retention, and long-term electrochemical stability, supporting glucose, lactate, and cholesterol detection in portable POCT systems.
Enzymes for Environmental Monitoring
Our enzymes are also employed in environmental diagnostics, such as detection of heavy metals, pesticides, and organic pollutants. Enzymes are engineered for performance under varying pH and temperature conditions encountered in field testing.
Enzymes for Food Safety Testing
We provide enzyme reagents for the detection of foodborne contaminants and quality indicators, including peroxidase and catalase for peroxide determination and glucose oxidase for fermentation monitoring.
Enzymes for Companion Diagnostics (CDx)
Creative Enzymes supports companion diagnostic assay development through customized enzyme validation in biomarker-linked tests co-developed with therapeutic partners, ensuring clinical reliability and regulatory readiness.
For emerging and niche diagnostic applications, Creative Enzymes offers custom enzyme sourcing and screening services, enabling rapid integration of enzyme components into novel assay formats.
Creative Enzymes categorizes enzymes according to catalytic class, providing researchers with mechanistic diversity to support assay innovation and kinetic optimization.
Hydrolases – including esterases, proteases, and phosphatases, essential for substrate cleavage in metabolic assays.
Isomerases – enabling structural rearrangements for carbohydrate and amino acid metabolism assays.
Ligases – used in nucleic acid ligation and repair-based molecular diagnostics.
Lyases – catalyzing bond cleavage without hydrolysis; applied in creatinine and urea assays.
Oxidoreductases – including dehydrogenases and oxidases, central to colorimetric and electrochemical detection systems.
Transferases – such as kinases and transaminases, critical in liver function and energy metabolism assays.
Each enzyme class is available in native, recombinant, and engineered forms, with activity validation, purity >95%, endotoxin < 0.1 EU/mg, and stability testing across multiple temperature and buffer systems.
Creative Enzymes focuses on providing core enzymatic components that serve as the foundation for developing high-performance biochemical assay kits. Our enzymes are optimized for integration into diagnostic reagent systems, ensuring high activity, substrate specificity, and long-term stability across diverse assay platforms.
Each enzyme is produced under strict quality control and validated for compatibility with clinical chemistry analyzers, POCT devices, and automated reagent systems. This allows diagnostic developers to design robust and reproducible assays with minimal optimization effort.
Below are representative categories of enzymes we supply for diagnostic kit development:
Creatininase, Creatinase, and Sarcosine Oxidase form the classic multi-enzyme cascade used for creatinine quantification in renal function panels.
Homocysteine Detection Enzymes
S-adenosylhomocysteine Hydrolase, Cystathionine β-synthase, and related enzymes enable enzymatic cycling assays with high sensitivity and low background.
N-Acetylneuraminic Acid Aldolase and N-Acetylneuraminate Lyase provide selective catalysis for total or bound sialic acid determination.
Triglyceride Quantification Enzymes
Lipase, Glycerol Kinase, and Glycerol-3-Phosphate Oxidase are supplied in diagnostic-grade purity for reliable lipid metabolism analysis.
Creatine Kinase (CK) Related Enzymes
Hexokinase and Glucose-6-Phosphate Dehydrogenase are available for CK-linked assays, ensuring linearity and precision.
Cholesterol Esterase and Cholesterol Oxidase catalyze sequential hydrolysis and oxidation steps, suitable for colorimetric or fluorometric assay formats.
Free Fatty Acid Determination Enzymes
Acyl-CoA Synthetase and Acyl-CoA Oxidase support coupled detection systems for FFA assays with excellent repeatability.
By choosing Creative Enzymes as your enzyme partner, diagnostic manufacturers gain access to high-consistency enzymatic reagents, enabling faster kit development, improved lot-to-lot reproducibility, and simplified regulatory validation.
Creative Enzymes also provides custom conjugates and hybrid biomolecules to support next-generation diagnostic assay design.
We manufacture enzyme–antibody conjugates such as HRP-, ALP-, and G6PD-labeled antibodies for ELISA, chemiluminescent, and lateral-flow assays. Each conjugate undergoes controlled coupling, purification, and activity validation, ensuring high signal-to-noise ratios and consistent labeling efficiency.
Creative Enzymes delivers molecular-grade enzymes used in PCR, qPCR, RT-PCR, and next-generation sequencing (NGS) workflows. All products are manufactured under ISO9001 and ISO13485-aligned processes.
PCR Enzymes and Premixes
High-fidelity and hot-start polymerases, reverse transcriptases, and master mixes designed for clinical and research diagnostics. Products are tested for amplification efficiency, residual nuclease contamination, and lot-to-lot consistency.
NGS Enzymes and Reagents
Comprehensive enzyme systems for library preparation, DNA/RNA fragmentation, ligation, and repair. These reagents exhibit high processivity, thermal stability, and inhibitor tolerance, supporting accurate sequencing library generation.
All Creative Enzymes diagnostic products undergo multilayer quality assurance, including:
We ensure that every product is research-use only (RUO) and optimized for diagnostic assay development and validation, not for clinical or therapeutic use.
Q1. Are Creative Enzymes products suitable for clinical use?
Q2. What purity and quality levels can be expected?
Q3. Can I order custom formulations or bulk quantities?
Q4. How are the enzymes stored and shipped?
Q5. Do you provide technical support for assay development?
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