| Cat# | BDE-052 |
| Description | N-acetylneuraminic acid aldolase (NAL) converts N-acetylneuraminic acid to N-acetyl-D-mannosamine and pyruvate. Sialic acid (SA) is a key tumor marker, and enzymatic SA detection is rapid, sensitive, and automatable. NAL is a critical enzyme in SA assay kits, where pyruvate generation drives the detection reaction. |
| Applications | Used in sialic acid detection kits for the analysis of tumor and inflammation-related biomarkers. |
| Enzyme Commission Number | EC 4.1.3.3 |
| Form | White lyophilized powder |
| Source | Recombinant protein expression |
| Activity | 33 U/mg |
| Unit Definition | One unit is defined as the amount of enzyme required to catalyze the reaction of N-acetylneuraminic acid to produce 1 μmol of pyruvate per minute under specified assay conditions (pH 7.7, 37 °C). |
| Molecular Weight | 35 kDa (SDS-PAGE) |
| Purity | ≥ 90% by SDS-PAGE |
| Storage Buffer | 100 mM phosphate buffer, pH 7.4 |
| Storage | Store at 4°C for one year; store at -20°C for two years (it is recommended to store in aliquots to avoid repeated freeze-thaw cycles that may affect protein activity). |
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