| Cat# | DIA-667 |
| Descriptions | Carbohydrate Sulfotransferase 10 (CHST10) specifically catalyzes 3-O-sulfation of glucuronic acid residues in the HNK-1 glycan epitope, regulates neural cell adhesion and migration, and supports research on nervous system development and neural regeneration. |
| Applications | Carbohydrate Sulfotransferase 10 (CHST10) serves as a key raw material for HNK-1 epitope detection kits and neural cell adhesion assay reagent development. |
| CAS No. | 28-2-1734 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived human Carbohydrate Sulfotransferase 10/CHST10 protein. |
| Reaction | 3′-phosphoadenylyl sulfate + 3-O-{beta-D-GlcA- (1->[3)-alpha-D-Xyl- (1->3)-beta-D-GlcA- (1->] (n)-4)-beta-D-Xyl- (1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc- (1->3)-beta-D-GlcNAc- (1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] = 3-O-{O-3-S-beta-D-GlcA- (1->[3)-alpha-D-Xyl- (1->3)-beta-D-GlcA- (1->] (n)-4)-beta-D-Xyl- (1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc- (1->3)-beta-D-GlcNAc- (1->4)-O-6-P-alpha-D-Man}-L-Thr-[protein] + adenosine 3′, 5′-bisphosphate + H+ |
| Activity Definition | Measured by its ability to transfer sulfate from PAPS to phenolpthalein glucuronic acid under the described conditions. |
| Download Datasheet: |  |
