| Cat# |
DIA-670 |
| Descriptions |
Carbohydrate Sulfotransferase 3 (CHST3) is responsible for 6-O-sulfation of N-acetylgalactosamine in chondroitin sulfate, plays a critical role in cartilage development and extracellular matrix function, and supports research on skeletal dysplasia mechanisms. |
| Applications |
Carbohydrate Sulfotransferase 3 (CHST3) serves as a core tool for chondroitin sulfate detection kit development and skeletal dysplasia related assay reagent development. |
| CAS No. |
28-2-1729 |
| Enzyme Commission Number |
EC 2.8.2.17 |
| Enzyme Source |
Chinese Hamster Ovary cell line, CHO-derived human Carbohydrate Sulfotransferase 3/CHST3 protein. |
| Reaction |
n 3′-phosphoadenylyl sulfate + chondroitin beta-D-glucuronate = n adenosine 3′, 5′-bisphosphate + chondroitin 6′-sulfate + 2 H+ |
| Activity Definition |
Measured by its ability to transfer sulfate from PAPS to chondroitin sulfate under the described conditions. |
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