| Cat# | DIA-710 |
| Descriptions | Fucosyltransferase 7 (FUT7) is specifically responsible for synthesizing sialyl Lewis x epitopes on leukocyte surface glycoproteins, mediates selectin-dependent cell adhesion during inflammatory response, and is a key target for immunology and anti-inflammatory drug research. |
| Applications | Fucosyltransferase 7 (FUT7) serves as a key raw material for sialyl Lewis x antigen detection kits and inflammatory cell adhesion assay reagent development. |
| CAS No. | 24-1-15222 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived human Fucosyltransferase 7/FUT7 protein. |
| Reaction | an N-acetyl-alpha-neuraminyl- (2->3)-beta-D-galactosyl- (1->4)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = an alpha-Neu5Ac- (2->3)-beta-D-Gal- (1->4)-[alpha-L-Fuc- (1->3)]-beta-D-GlcNAc derivative + GDP + H+ |
| Activity Definition | Measured by its ability to transfer fucose from GDP-fucose to fetal bovine fetuin. |
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