| Cat# | DIA-724 |
| Descriptions | Glucosamine (N-acetyl)-6-Sulfatase (GNS) is a lysosomal sulfatase that hydrolyzes 6-O-sulfate groups from N-acetylglucosamine residues in heparan sulfate, mediates glycosaminoglycan catabolism, and is the pathogenic enzyme of mucopolysaccharidosis type IIID. |
| Applications | Glucosamine (N-acetyl)-6-Sulfatase (GNS) is widely used in mucopolysaccharidosis type IIID detection kits and glycosaminoglycan metabolism assay reagent development. |
| CAS No. | 31-6-1463 |
| Enzyme Commission Number | EC 3.1.6.14 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived human Glucosamine (N-acetyl)-6-Sulfatase/GNS protein. |
| Reaction | Hydrolysis of the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate. |
| Activity Definition | Measured by its ability to hydrolyze the substrate 4-Nitrocatechol Sulfate (PNCS) under the described conditions. |
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