| Cat# | DIA-726 |
| Descriptions | Glucosaminyl (N-acetyl) Transferase 2 (GCNT2) functions as the I-branching enzyme that introduces β1,6-linked GlcNAc branches into poly-N-acetyllactosamine chains, converts fetal i antigen to adult I antigen, and regulates erythrocyte surface glycan expression during development. |
| Applications | Glucosaminyl (N-acetyl) Transferase 2 (GCNT2) is used for I blood group antigen detection kits and erythrocyte glycan assay reagent development. |
| CAS No. | 24-1-1508 |
| Enzyme Commission Number | EC 2.4.1.150 |
| Enzyme Source | CHO-derived |
| Reaction | a beta-D-Gal- (1->4)-beta-D-GlcNAc- (1->3)-beta-D-Gal- (1->4)-beta-D-GlcNAc derivative + UDP-N-acetyl-alpha-D-glucosamine = a beta-D-Gal- (1->4)-beta-D-GlcNAc- (1->3)-[beta-D-GlcNAc- (1->6)]-beta-D-Gal- (1->4)-N-acetyl-beta-D-glucosaminyl derivative + H+ + UDP |
| Activity Definition | Measured by its ability to transfer GlcNAc from UDP-GlcNAc to Cy5-labeled Extended G2. |
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