Guanylate kinase (ScGMK) derived from Saccharomyces cerevisiae mediates the reversible phosphorylation of GMP to GDP using ATP as phosphate donor, is a key enzyme in guanine nucleotide metabolism, and is applied for GTP regeneration and nucleic acid biosynthesis studies.
Applications
Guanylate kinase (ScGMK) is used for guanine nucleotide metabolism detection kits and GTP regeneration system reagent development.
CAS No.
127-4-81
Enzyme Commission Number
EC 2.7.4.8
Enzyme Source
E.coli recombinant Sc GMK from Salmonella choleraesuis.
Reaction
ATP + GMP = ADP + GDP
Activity Definition
One unit is defined as the amount of enzyme that catalyzes the formation of 1 μmol of GDP from GMP and ATP at 37°C.