| Cat# |
TRA-324 |
| Specification |
5μg(min) |
| Description |
The cytoplasmic domain of human KIT was produced as an N-terminal GST fusion protein 76 kDa using a baculovirus expression system. GST-KIT was isolated via glutathione sepharose chromatography. |
| Applications |
For use as a positive control in KIT mutation detection assays for GIST and melanoma companion diagnostics. |
| Synonyms |
KIT, C-Kit, CD117, MASTC, PBT, SCFR |
| Source |
Insect (sf21) |
| Molecular Weight |
76 kDa |
| Class |
Receptor Tyrosine Kinase |
| Group |
TK |
| Family |
PDGFR |
| Gene Name |
KIT | KIT proto-oncogene, receptor tyrosine kinase |
| Sequence |
544-976 (end) |
| Accession Number |
NP_000213.1 |
| Tag |
GST-Tag |
| Tag Location |
N-terminal GST |
| Storage Buffer |
50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35,1 mM DTT, 10% glycerol, pH 7.5 |
| Storage |
Store at -80°C. Avoid repeating freeze-thaws. |
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