| Cat# | DIA-771 |
| Descriptions | N-Acetylglucosaminyltransferase 2 (MGAT2), also designated as GnT-II, transfers N-acetylglucosamine to the α-1,6 mannose arm of N-glycans, initiates biantennary complex N-glycan formation, and is essential for mature N-glycan biosynthesis. |
| Applications | N-Acetylglucosaminyltransferase 2 (MGAT2) is used for biantennary complex N-glycan detection kits and N-glycan maturation assay reagent development. |
| CAS No. | 24-1-14310 |
| Enzyme Commission Number | EC 2.4.1.143 |
| Enzyme Source | Human embryonic kidney cell, HEK293-derived human N-Acetylglucosaminyltransferase 2/MGAT2 protein. |
| Reaction | N4-{beta-D-GlcNAc- (1->2)-alpha-D-Man- (1->3)-[alpha-D-Man- (1->6)]-beta-D-Man- (1->4)-beta-D-GlcNAc- (1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = H+ + N4-{beta-D-GlcNAc- (1->2)-alpha-D-Man- (1->3)-[beta-D-GlcNAc- (1->2)-alpha-D-Man- (1->6)]-beta-D-Man- (1->4)-beta-D-GlcNAc- (1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP |
| Activity Definition | Measured by its ability to modify the glycan Cy5-labeled M1N1f and thereby creating a band shift. |
| Download Datasheet: |  |
