| Cat# | DIA-779 |
| Descriptions | N-Deacetylase/N-Sulfotransferase 2 (NDST2) is a predominant isoform in mast cells that mediates highly sulfated heparin biosynthesis, generates tissue-specific heparan sulfate structures, and regulates storage and release of mast cell granule components. |
| Applications | N-Deacetylase/N-Sulfotransferase 2 (NDST2) serves as a raw material for heparin biosynthesis detection kits and mast cell granule component assay reagent development. |
| Enzyme Commission Number | EC 2.8.2.8 |
| Enzyme Source | Human embryonic kidney cell, HEK293-derived human N-Deacetylase/N-Sulfotransferase 2/NDST2 protein. |
| Reaction | 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate] (n) = adenosine 3', 5'-bisphosphate + 2 H+ + N-sulfo-alpha-D-glucosaminyl-[heparan sulfate] (n) |
| Activity Definition | Measured by its ability to transfer sulfate from PAPS to heparan sulfate under the described conditions. |
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