| Cat# | DIA-864 |
| Descriptions | ST3 Beta-Gal Alpha-2, 3-Sialyltransferase 5 (ST3GAL5/GM3 Synthase, Mouse) is the key enzyme for ganglioside GM3 biosynthesis, catalyzes α-2,3 sialylation of lactosylceramide, and regulates cell proliferation, differentiation and signal transduction pathways. |
| Applications | ST3 Beta-Gal Alpha-2, 3-Sialyltransferase 5 (ST3GAL5/GM3 Synthase, Mouse) is suitable for ganglioside GM3 detection kits and cell signal transduction assay reagent development. |
| CAS No. | 24-3-91305 |
| Enzyme Commission Number | EC 2.4.3.9 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived mouse ST3GAL5/GM3 Synthase protein. |
| Reaction | a beta-D-Gal- (1->4)-beta-D-Glc- (1->1)-Cer (d18:1 (4E)) + CMP-N-acetyl-beta-neuraminate = CMP + ganglioside GM3 (d18:1 (4E)) + H+ |
| Activity Definition | Measured by its ability to transfer Neu5Ac from CMP-Neu5Ac to alpha -lactose. |
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