| Cat# | DIA-868 |
| Descriptions | ST6 Sialyltransferase 1 (ST6GALNAC1) specifically transfers sialic acid via α-2,6 linkage to N-acetylgalactosamine residues of O-linked glycans, synthesizes sialyl Tn antigen, and is closely associated with tumor malignancy and metastatic potential. |
| Applications | ST6 Sialyltransferase 1 (ST6GALNAC1) is suitable for sialyl Tn antigen detection kits and tumor malignancy assay reagent development. |
| CAS No. | 24-3-31309 |
| Enzyme Commission Number | EC 2.4.3.3 |
| Enzyme Source | Human embryonic kidney cell, HEK293-derived human ST6 Sialyltransferase 1/ST6GALNAC1 protein. |
| Reaction | a beta-D-galactosyl- (1->3)-N-acetyl-alpha-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = a beta-D-galactosyl- (1->3)-[N-acetyl-alpha-neuraminyl- (2->6)]-N-acetyl-alpha-D-galactosaminyl derivative + CMP + H+ |
| Activity Definition | Measured by its ability to transfer Neu5Ac from CMP-Neu5Ac to fetuin of fetal calf serum. |
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