| Cat# |
DIA-885 |
| Descriptions |
Tissue Alpha-L-Fucosidase (FUCA1) is a lysosomal glycosidase that specifically hydrolyzes α-L-fucose residues from various glycoconjugates, participates in glycoprotein and glycolipid catabolism, and its deficiency causes fucosidosis, a lysosomal storage disorder. |
| Applications |
Tissue Alpha-L-Fucosidase (FUCA1) is used for fucosidosis related detection kits and lysosomal glycoconjugate metabolism assay reagent development. |
| CAS No. |
32-1-5150 |
| Enzyme Commission Number |
EC 3.2.1.51 |
| Enzyme Source |
Trichoplusia ni, High Five (baculovirus)-derived human Tissue alpha-L-Fucosidase/FUCA1 protein. |
| Reaction |
an alpha-L-fucoside + H2O = an alcohol + L-fucose |
| Activity Definition |
Measured by its ability to cleave a fluorogenic substrate 4-methylumbelliferyl-alpha -L-fucopyranoside. |
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