| Cat# | DIA-645 |
| Descriptions | Beta-1, 4-Glucuronyltransferase 1 (B4GAT1) catalyzes β-1,4 linked glucuronic acid addition to galactose residues, participates in the formation of proteoglycan tetrasaccharide linkers, and plays an important role in glycosaminoglycan biosynthesis and extracellular matrix research. |
| Applications | Beta-1, 4-Glucuronyltransferase 1 (B4GAT1) is applied in proteoglycan linker region detection kit development and extracellular matrix glycan assay reagent preparation. |
| CAS No. | 24-2-13547 |
| Enzyme Source | CHO-derived |
| Reaction | 3-O-[beta-D-Xyl- (1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc- (1->3)-beta-D-GlcNAc- (1->4)- (O-6-P-alpha-D-Man)]-Thr-[protein] + UDP-alpha-D-glucuronate = 3-O-[beta-D-GlcA- (1->3)-beta-D-Xyl- (1->4)-Rib-ol-P-Rib-ol-P-3-beta-D-GalNAc- (1->3)-beta-D-GlcNAc- (1->4)- (O-6-P-alpha-D-Man)]-Thr-[protein] + H+ + UDP |
| Activity Definition | Measured by its ability to transfer GlcA from UDP-GlcA to Xylose. |
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