| Cat# |
DIA-672 |
| Descriptions |
Carbohydrate Sulfotransferase 5 (CHST5) exhibits restricted expression in gastrointestinal tissues, catalyzes 6-O-sulfation of mucosal O-glycan N-acetylglucosamine, and participates in maintaining intestinal mucosal barrier function and innate immunity. |
| Applications |
Carbohydrate Sulfotransferase 5 (CHST5) is suitable for gastrointestinal mucosal O-glycan detection kits and mucosal barrier function assay reagent development. |
| CAS No. |
28-2-1731 |
| Enzyme Source |
Chinese Hamster Ovary cell line, CHO-derived mouse Carbohydrate Sulfotransferase 5/CHST5 protein. |
| Reaction |
Sulfotransferase that utilizes 3′-phospho-5′-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues and O-linked sugars of mucin-type acceptors. |
| Activity Definition |
Measured by its ability to transfer sulfate from PAPS to N-acetyl-D-glucosamine under the described conditions. |
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