| Cat# | DIA-863 |
| Descriptions | ST3 Beta-Gal Alpha-2, 3-Sialyltransferase 4 (ST3GAL4) is responsible for α-2,3 sialylation of serum glycoproteins and selectin ligands, participates in inflammatory cell recruitment, and is closely associated with tumor metastasis and liver glycosylation regulation. |
| Applications | ST3 Beta-Gal Alpha-2, 3-Sialyltransferase 4 (ST3GAL4) is applied in selectin ligand detection kits and inflammatory cell recruitment assay reagent development. |
| CAS No. | 24-3-21304 |
| Enzyme Commission Number | EC 2.4.3.2 |
| Enzyme Source | Trichoplusia ni, High Five (baculovirus)-derived human ST3GAL4 protein. |
| Reaction | a beta-D-galactosyl- (1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl- (2->3)-beta-D-galactosyl- (1->3)-N-acetyl-beta-D-galactosaminyl derivative + CMP + H+ |
| Activity Definition | Measured by its ability to transfer Neu5Ac from CMP-Neu5Ac to alpha -lactose. |
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