| Cat# |
DIA-707 |
| Descriptions |
Fucosyltransferase 3 (FUT3) possesses both α-1,4 and α-1,3 fucosyltransferase activities, mediates the synthesis of Lewis blood group antigens including Le (a) and Le (b), and is widely applied in antigen preparation and tumor-associated glycan research. |
| Applications |
Fucosyltransferase 3 (FUT3) is widely used in Lewis blood group antigen detection kits and tumor-associated glycan assay reagent development. |
| CAS No. |
24-1-65319 |
| Enzyme Commission Number |
EC 2.4.1.65 |
| Enzyme Source |
Trichoplusia ni, High Five (baculovirus)-derived human Fucosyltransferase 3/FUT3 protein. |
| Reaction |
a beta-D-galactosyl- (1->3)-N-acetyl-beta-D-glucosaminyl derivative + GDP-beta-L-fucose = a beta-D-galactosyl- (1->3)-[alpha-L-fucosyl- (1->4)]-N-acetyl-beta-D-glucosaminyl derivative + GDP + H+ |
| Activity Definition |
Measured by its ability to transfer fucose from GDP-fucose to N-Acetyllactosamine. |
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