| Cat# | DIA-741 |
| Descriptions | Heparan Sulfate 3-O-Sulfotransferase 1 (HS3ST1) catalyzes 3-O-sulfation of glucosamine residues in heparan sulfate to generate antithrombin-binding pentasaccharide domains, confers anticoagulant activity, and is a core enzyme for bioengineered heparin biosynthesis. |
| Applications | Heparan Sulfate 3-O-Sulfotransferase 1 (HS3ST1) is suitable for anticoagulant heparin detection kits and antithrombin binding domain assay reagent development. |
| CAS No. | 28-02-2338 |
| Enzyme Commission Number | EC 2.8.2.23 |
| Enzyme Source | CHO-derived |
| Reaction | 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate] (n) = 3-sulfo-alpha-D-glucosaminyl-[heparan sulfate] (n) + adenosine 3', 5'-bisphosphate + H+ |
| Activity Definition | Measured by its ability to transfer sulfate from PAPS to heparan sulfate. The specific activity is >30 pmol/min/μg, as measured under the described conditions. |
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