GlcNAc-1-Phosphotransferase (GNPTAB & GNPTG) is a multisubunit enzyme complex composed of GNPTAB and GNPTG subunits, which mediates mannose-6-phosphate tagging on lysosomal hydrolases to ensure correct lysosomal sorting, and is a critical research target for mucolipidosis type II and III disorders.
Applications
GlcNAc-1-Phosphotransferase (GNPTAB & GNPTG) serves as a raw material for lysosomal enzyme sorting detection kits and mucolipidosis related assay reagent development.
Enzyme Source
Trichoplusia ni, High Five (baculovirus)-derived human Glc NAc-1-Phosphotransferase protein.