| Cat# | DIA-731 |
| Descriptions | Glucosylceramidase (GBA) is a lysosomal β-glucosidase that hydrolyzes glucosylceramide into glucose and ceramide to maintain glycosphingolipid metabolic homeostasis, is the deficient enzyme in Gaucher disease, and is a core target for enzyme replacement therapy research. |
| Applications | Glucosylceramidase (GBA) is suitable for Gaucher disease related detection kits and glycosphingolipid metabolism assay reagent development. |
| CAS No. | 32-1-4552 |
| Enzyme Commission Number | EC 3.2.1.45 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived human Glucosylceramidase/GBA protein. |
| Reaction | a beta-D-glucosyl- (1->1′)-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-glucose |
| Activity Definition | Measured by its ability to hydrolyze 4-methylumbelliferyl-beta -D-glucopyranoside. |
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