| Cat# | DIA-746 |
| Descriptions | Heparanase (HPSE) is an endo-β-glucuronidase that cleaves internal glycosidic bonds in heparan sulfate chains of the extracellular matrix, promotes matrix remodeling and angiogenesis, and is recognized as a key therapeutic target for tumor metastasis and inflammatory diseases. |
| Applications | Heparanase (HPSE) is suitable for tumor metastasis detection kits and extracellular matrix remodeling assay reagent development. |
| CAS No. | 32-1-16653 |
| Enzyme Commission Number | EC 3.2.1.166 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived human Heparanase/HPSE protein. |
| Reaction | Endohydrolysis of (1->4)-beta-D-glycosidic bonds of heparan sulfate chains in heparan sulfate proteoglycan. |
| Activity Definition | Measured by its ability to release biotinylated heparan sulfate from Recombinant Human Syndecan-4. |
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