![Human PDGFRα [T674I] Protein (GST-Tag), Recombinant](https://diagnostic-enzymes.creative-enzymes.com/wp-content/themes/diagnostic-enyzmes/images/nomain-banner-Single-Strain-2.jpg)
| Cat# | TRA-363 |
| Specification | 5μg(min) |
| Description | The cytoplasmic domain of human PDGFRα containing the T674I mutation was expressed as an N-terminal GST fusion protein 89 kDa employing a baculovirus expression system. GST-PDGFRα [T674I] was purified by glutathione sepharose chromatography. |
| Applications | For use in research assays for PDGFRA T674I resistance to multi-kinase inhibitors. |
| Synonyms | PDGFRA, CD140A, PDGFR-2, PDGFR2, CD140a |
| Source | Insect (sf21) |
| Molecular Weight | 89 kDa |
| Class | Receptor Tyrosine Kinase |
| Group | TK |
| Family | PDGFR |
| Gene Name | PDGFRA | platelet derived growth factor receptor alpha |
| Sequence | 550-1089 (end) |
| Accession Number | NP_006197.1 |
| Tag | GST-Tag |
| Tag Location | N-terminal GST |
| Storage Buffer | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35,1 mM DTT, 10% glycerol, pH 7.5 |
| Storage | Store at -80°C. Avoid repeating freeze-thaws. |
| Download Datasheet: |  |
