| Cat# | DIA-764 |
| Descriptions | Lysosomal Alpha-mannosidase (MAN2B1) catalyzes the hydrolysis of α-linked mannose residues in N-linked glycoprotein oligosaccharides during lysosomal glycoprotein degradation, and its functional deficiency causes alpha-mannosidosis, a lysosomal storage disorder. |
| Applications | Lysosomal Alpha-mannosidase (MAN2B1) is suitable for alpha-mannosidosis detection kits and lysosomal glycoprotein degradation assay reagent development. |
| CAS No. | 32-1-2459 |
| Enzyme Commission Number | EC 3.2.1.24 |
| Enzyme Source | Human embryonic kidney cell, HEK293-derived human MAN2B1 protein. |
| Reaction | Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides. |
| Activity Definition | Measured by its ability to hydrolyze 4-methylumbelliferyl-alpha -D-mannopyranoside under the described conditions. |
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