| Cat# | DIA-873 |
| Descriptions | ST8 Alpha-2, 8-Sialyltransferase 4 (ST8SIA4) catalyzes the formation of α-2,8 linked polysialic acid chains on neural cell adhesion molecules, modulates cell-cell adhesion during neural development, and supports polysialic acid modification research. |
| Applications | ST8 Alpha-2, 8-Sialyltransferase 4 (ST8SIA4) is used for polysialic acid detection kits and neural cell adhesion assay reagent development. |
| CAS No. | 24-09-9316 |
| Enzyme Source | CHO-derived |
| Reaction | Catalyzes the polycondensation of alpha-2, 8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. |
| Activity Definition | Measured by its ability to transfer sialic acid from CMP-NeuAc to Recombinant Human NCAM-1/CD56 120 isoform. |
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