| Cat# | DIA-875 |
| Descriptions | ST8 Alpha-2, 8-Sialyltransferase 8A (ST8SIA1), also known as GD3 synthase, catalyzes the addition of α-2,8 linked sialic acid to GM3 to form GD3 ganglioside, is essential for b-series ganglioside biosynthesis, and regulates neural cell development and tumor progression. |
| Applications | ST8 Alpha-2, 8-Sialyltransferase 8A (ST8SIA1) is applied in GD3 ganglioside detection kits and b-series ganglioside biosynthesis assay reagent development. |
| CAS No. | 24-4-81314 |
| Enzyme Commission Number | EC 2.4.3.8 |
| Enzyme Source | CHO-derived |
| Reaction | an N-acetyl-alpha-neuraminyl- (2->3)-beta-D-galactosyl derivative + CMP-N-acetyl-beta-neuraminate = an N-acetyl-alpha-neuraminyl- (2->8)-N-acetyl-alpha-neuraminyl- (2->3)-beta-D-galactosyl derivative + CMP + H+ |
| Activity Definition | Measured by its ability to transfer Neu5Ac from CMP-Neu5Ac to fetuin of fetal calf serum. |
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