| Cat# | DIA-876 |
| Descriptions | ST8 Alpha-2, 8-Sialyltransferase 8B (ST8SIA2) is a polysialyltransferase that assembles long α-2,8 polysialic acid chains on glycoprotein acceptors, is predominantly expressed in the nervous system, and modulates neural cell migration and axon guidance. |
| Applications | ST8 Alpha-2, 8-Sialyltransferase 8B (ST8SIA2) is suitable for polysialic acid modification detection kits and neural development assay reagent development. |
| CAS No. | 24-3-81315 |
| Enzyme Source | Trichoplusia ni, High Five (baculovirus)-derived human ST8 alpha-2,8-Sialyltra. |
| Reaction | May transfer sialic acid through alpha-2, 8-linkages to the alpha-2, 3-linked and alpha-2, 6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression. |
| Activity Definition | Measured by its ability to transfer sialic acid from CMP-NeuAc to Recombinant Human NCAM‑1/CD56 120 isoform. |
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