| Cat# | DIA-888 |
| Descriptions | Tyrosylprotein Sulfotransferase 2 (TPST2) exhibits distinct substrate specificity from TPST1, catalyzes tyrosine sulfation of specific protein substrates including chemokine receptors and coagulation factors, and modulates immune response and hemostatic processes. |
| Applications | Tyrosylprotein Sulfotransferase 2 (TPST2) is suitable for immune receptor sulfation detection kits and coagulation function assay reagent development. |
| CAS No. | 28-02-2067 |
| Enzyme Commission Number | EC 2.8.2.20 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived human Tyrosylprotein Sulfotransferase 2/TPST2 protein. |
| Reaction | 3′-phosphoadenylyl sulfate + L-tyrosyl-[protein] = adenosine 3′, 5′-bisphosphate + H+ + O-sulfo-L-tyrosine-[protein] |
| Activity Definition | Measured by its ability to transfer sulfate from PAPS to PSGL-1 peptide (Gln-Ala-Thr-Glu-Tyr-Glu-Tyr-Leu-Asp-Tyr-Asp-Phe-Leu-Pro-Glu-Thr) under the described conditions. |
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