| Cat# | NATE-0032 |
| Source | E. coli |
| Description | Adenosine deaminase is an enzyme (EC 3.5.4.4) involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. Present in virtually all mammalian cells, its primary function in Humans is the development and maintenance of the immune system. |
| Form | ammonium sulfate suspension. Suspension in 3.2 M (NH4)2SO4, 0.01 M potassium phosphate, pH 6.0 |
| Activity | 60-130 units/mg protein; > 130 units/mg protein; 150-200 units/mg protein |
| CAS No. | 9026-93-1 |
| Isoelectric point | 4.85 |
| Unit Definition | One unit will deaminate 1.0 μmole of adenosine to inosine per min at pH 7.5 at 25°C. |
| Storage | 2-8°C |
| Synonyms | ADA; adenosine deaminase; adenosine aminohydrolase; 9026-93-1; EC 3.5.4.4 |
| Enzyme Commission Number | EC 3.5.4.4 |
| Abbr | ADA, Recombinant (Bovine) |
| Alias | ADA; adenosine deaminase |
| Applications | Adenosine deaminase is useful in various molecular biology assays, such as glycerol release assays. Adenosine deaminase is a potential target for treatments of combined immunodeficiency disease. |
| Product Overview | Protein determined by biuret. |
| Molecular Weight | 32.5-33 kDa |
| Species | Bovine |
| Pathway | Metabolic pathways, organism-specific biosystem; Primary immunodeficiency, organism-specific biosystem; Purine metabolism, conserved biosystem |
| Function | adenosine deaminase activity; protein binding; zinc ion binding |
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