| Cat# |
DIA-637 |
| Descriptions |
Beta-1, 3-Glucuronyltransferase 1 (B3GAT1) specifically transfers glucuronic acid to form β-1,3 glycosidic linkages, is responsible for the biosynthesis of the HNK-1 carbohydrate epitope, and is extensively used in neural glycan research and functional oligosaccharide preparation. |
| Applications |
Beta-1, 3-Glucuronyltransferase 1 (B3GAT1) is applied in HNK-1 glycan epitope detection kit development and neural glycan assay reagent development. |
| CAS No. |
24-2-13546 |
| Enzyme Commission Number |
EC 2.4.1.135 |
| Enzyme Source |
CHO-derived |
| Reaction |
3-O- (beta-D-galactosyl- (1->3)-beta-D-galactosyl- (1->4)-beta-D-xylosyl)-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O- (beta-D-GlcA- (1->3)-beta-D-Gal- (1->3)-beta-D-Gal- (1->4)-beta-D-Xyl)-L-seryl-[protein] + H+ + UDP |
| Activity Definition |
Measured by its ability to transfer GlcA from UDP-GlcA to lactose. |
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