| Cat# |
DIA-666 |
| Descriptions |
Carbohydrate Sulfotransferase 1 (CHST1) transfers sulfate groups to position 6 of galactose residues in keratan sulfate, mediates sulfated glycosaminoglycan maturation, and is essential for studying cartilage extracellular matrix formation and related skeletal diseases. |
| Applications |
Carbohydrate Sulfotransferase 1 (CHST1) is suitable for keratan sulfate detection kit development and cartilage extracellular matrix assay reagent development. |
| Enzyme Commission Number |
EC 2.8.2.21 |
| Enzyme Source |
Chinese Hamster Ovary cell line, CHO-derived human Carbohydrate Sulfotransferase 1/CHST1 protein. |
| Reaction |
3′-phosphoadenylyl sulfate + keratan = adenosine 3′, 5′-bisphosphate + keratan 6′-sulfate. |
| Activity Definition |
Measured by its ability to transfer sulfate from PAPS to alpha -Lactose under the described conditions. |
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