| Cat# | DIA-671 |
| Descriptions | Carbohydrate Sulfotransferase 4 (CHST4) specifically sulfates N-acetylglucosamine residues at position 6 in peripheral node addressin glycans, mediates lymphocyte adhesion to high endothelial venules, and is key for studying immune cell trafficking and mucosal immunity. |
| Applications | Carbohydrate Sulfotransferase 4 (CHST4) is widely used in peripheral node addressin detection kits and immune cell trafficking assay reagent development. |
| CAS No. | 28-2-1730 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived human Carbohydrate Sulfotransferase 4/CHST4 protein. |
| Reaction | 3′-phosphoadenylyl sulfate + 3-O-{N-acetyl-beta-D-glucosaminyl- (1->3)-beta-D-galactosyl- (1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] = 3-O-{6-O-sulfo-N-acetyl-beta-D-glucosaminyl- (1->3)-beta-D-galactosyl- (1->3)-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + adenosine 3′, 5′-bisphosphate + H+ |
| Activity Definition | Measured by its ability to transfer sulfate from PAPS to N-acetyl-D-glucosamine under the described conditions. |
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