CMP-sialic acid synthetase (NmCSS) from Neisseria meningitidis catalyzes the formation of CMP-sialic acid from sialic acid and CTP, serves as a key enzyme for activated sialic acid donor synthesis, and supports large-scale sialylated glycan production.
Applications
CMP-sialic acid synthetase (NmCSS) serves as a key biocatalyst for sialic acid donor synthesis detection kits and large-scale sialylated glycan production assay reagent development.
CAS No.
127-7-43
Enzyme Commission Number
EC 2.7.7.43
Enzyme Source
Neisseria meningitidis.
Reaction
Neu5Ac + CTP = CMP-Neu5Ac + PPi
Activity Definition
One unit is defined as the amount of enzyme that catalyzes the formation of 1 Mumol CMP-Neu5Ac from CTP and Neu5Ac per minute at 37°C.