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Cystathionine-β-synthase, Recombinant

Cat# DIA-293
Description Cystathionine-β-synthase, also known as CBS, is an enzyme (EC 4.2.1.22) that in humans is encoded by the CBS gene. CBS uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. CBS is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The CBS gene is the most common locus for mutations associated with homocystinuria.
CAS No. 9023-99-8
Isoelectric point 6.49
Storage The lyophilized powder should be stored at -20°C where it is stable for up to several years. The solution could be stored at 4°C where it is stable for up to 1 year. Repeated freezing and thawing cycles of the reconstituted solution is not recommended .
Synonyms Cystathionine-β-synthase; CBS; EC 4.2.1.22; 9023-99-8
Enzyme Commission Number EC 4.2.1.22
Purity >90% (by SDS-PAGE)
pH Stability 7.4-8.5
Buffer PBS,pH7.4
Abbr CBS, Recombinant
Alias CBS
Applications This protein can be used for producing Hcy in vitro diagnosis Kit .
Appearance Lyophilized powder
Molecular Weight 56 KD
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