| Cat# | DIA-716 |
| Descriptions | Galactosylceramidase (GALC) is a lysosomal hydrolase that catalyzes the hydrolysis of galactosylceramide into galactose and ceramide, is responsible for glycosphingolipid catabolism, and is a key research object for Krabbe disease and lysosomal storage disorder mechanisms. |
| Applications | Galactosylceramidase (GALC) is used for Krabbe disease related detection kits and glycosphingolipid metabolism assay reagent development. |
| CAS No. | 32-1-4651 |
| Enzyme Commission Number | EC 3.2.1.46 |
| Enzyme Source | Chinese Hamster Ovary cell line, CHO-derived human Galactosylceramidase/GALC protein. |
| Reaction | a beta-D-galactosyl- (1->1′)-N-acylsphing-4-enine + H2O = an N-acylsphing-4-enine + D-galactose |
| Activity Definition | Measured by its ability to cleave a fluorogenic substrate, 4-Methylumbelliferyl-beta -D-galactopyranoside. |
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