| Cat# | DIA-743 |
| Descriptions | Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1) mediates 6-O-sulfation of glucosamine residues in heparan sulfate chains, modulates the binding affinity of growth factors and chemokines, and plays critical roles in embryonic development and angiogenesis regulation. |
| Applications | Heparan Sulfate 6-O-Sulfotransferase 1 (HS6ST1) serves as a tool for heparan sulfate 6-O-sulfation detection kits and angiogenesis related assay reagent development. |
| Enzyme Source | CHO-derived |
| Reaction | 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate] (n) = 6-sulfo-alpha-D-glucosaminyl-[heparan sulfate] (n) + adenosine 3', 5'-bisphosphate + H+ |
| Activity Definition | Measured by its ability to transfer sulfate from PAPS to heparan sulfate under the described conditions. |
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