| Cat# | TRA-128 |
| Specification | 10μg(min) |
| Description | The cytoplasmic domain of human ALK with I1461V, K1491R, and D1529E substitutions was generated as an N-terminal DYKDDDDK-tagged, biotinylated protein 67 kDa in a baculovirus expression system. The protein was purified using a combination of DYKDDDDK tag antibody agarose and gel filtration chromatography. |
| Applications | For use as a positive control in IHC or mass spectrometry-based assays for ALK fusion detection in NSCLC. |
| Synonyms | ALK, CD246, NBLST3 |
| Source | Insect (sf21) |
| Molecular Weight | 67 kDa |
| Class | Receptor Tyrosine Kinase |
| Group | TK |
| Family | Alk |
| Gene Name | ALK | ALK receptor tyrosine kinase |
| Sequence | 1058-1620 (end) |
| Accession Number | NP_004295.2 |
| Tag | BTN-Tag |
| Tag Location | N-terminal DYKDDDDK |
| Storage Buffer | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35,1 mM DTT, 10% glycerol, pH 7.5 |
| Storage | Store at -80°C. Avoid repeating freeze-thaws. |
| Download Datasheet: |  |
