| Cat# |
TRA-276 |
| Specification |
10μg(min) |
| Description |
The cytoplasmic domain of human FGFR3 was produced as an N-terminal DYKDDDDK-tagged, biotinylated protein 45 kDa using a baculovirus expression system. Following purification with DYKDDDDK tag antibody agarose and activation with ATP, the activated protein was isolated via gel filtration. |
| Applications |
For use as a positive control in FGFR3 mutation detection assays for bladder cancer and multiple myeloma diagnosis. |
| Synonyms |
FGFR3,ACH,CD333,CEK2,HSFGFR3EX,JTK4 |
| Source |
Insect (sf21) |
| Molecular Weight |
45 kDa |
| Class |
Receptor Tyrosine Kinase |
| Group |
TK |
| Family |
FGFR |
| Gene Name |
FGFR3 | fibroblast growth factor receptor 3 |
| Sequence |
436-806 (end) |
| Accession Number |
NP_000133.1 |
| Tag |
BTN-Tag |
| Tag Location |
N-terminal DYKDDDDK |
| Storage Buffer |
50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35,1 mM DTT, 10% glycerol, pH 7.5 |
| Storage |
Store at -80°C. Avoid repeating freeze-thaws. |
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