| Cat# |
TRA-305 |
| Specification |
5μg(min) |
| Description |
The cytoplasmic domain of human HER2, containing the P1170A variant, was produced as an N-terminally His-tagged protein 67 kDa using a baculovirus expression system. The His-tagged HER2 protein was isolated via Ni-NTA affinity chromatography. |
| Applications |
For use as a positive control in HER2 detection assays for breast and gastric cancer companion diagnostics. |
| Synonyms |
ERBB2, CD340, HER-2, HER-2/neu, HER2, MLN19, NEU, NGL, TKR1 |
| Source |
Insect (sf21) |
| Molecular Weight |
67 kDa |
| Class |
Receptor Tyrosine Kinase |
| Group |
TK |
| Family |
EGFR |
| Gene Name |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
| Sequence |
676-1255 (end) |
| Accession Number |
NP_004439.2 |
| Tag |
HIS-Tag |
| Tag Location |
N-terminal His |
| Storage Buffer |
50 mM Tris-HCl, 150 mM NaCl, 0.1% CHAPS,5 mM DTT, 10% glycerol, pH 7.5 |
| Storage |
Store at -80°C. Avoid repeating freeze-thaws. |
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