| Cat# | TRA-369 |
| Specification | 10μg(min) |
| Description | The cytoplasmic domain of human RET was produced as an N-terminal DYKDDDDK-tagged, biotinylated protein 56 kDa using a baculovirus expression system. After purification with DYKDDDDK tag antibody agarose and activation with ATP, the activated protein was isolated by gel filtration. |
| Applications | For use as a positive control in RET mutation detection assays for medullary thyroid carcinoma diagnosis. |
| Synonyms | RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51 |
| Source | Insect (sf21) |
| Molecular Weight | 56 kDa |
| Class | Receptor Tyrosine Kinase |
| Group | TK |
| Family | Ret |
| Gene Name | RET | ret proto-oncogene |
| Sequence | 658-1114 (end) |
| Accession Number | NP_066124.1 |
| Tag | BTN-Tag |
| Tag Location | N-terminal DYKDDDDK |
| Storage Buffer | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35,1 mM DTT, 10% glycerol, pH 7.5 |
| Storage | Store at -80°C. Avoid repeating freeze-thaws. |
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