| Cat# | DIA-778 |
| Descriptions | N-Deacetylase/N-Sulfotransferase 1 (NDST1) is a bifunctional enzyme that performs both N-deacetylation and subsequent N-sulfation of glucosamine residues in heparan sulfate precursor chains, determines the overall sulfation level, and shapes heparan sulfate functional domains. |
| Applications | N-Deacetylase/N-Sulfotransferase 1 (NDST1) is used for heparan sulfate sulfation detection kits and glycosaminoglycan biosynthesis assay reagent development. |
| CAS No. | 28-02-8043 |
| Enzyme Commission Number | EC 2.8.2.8 |
| Enzyme Source | CHO-derived |
| Reaction | 3'-phosphoadenylyl sulfate + alpha-D-glucosaminyl-[heparan sulfate] (n) = adenosine 3', 5'-bisphosphate + 2 H+ + N-sulfo-alpha-D-glucosaminyl-[heparan sulfate] (n) |
| Activity Definition | Measured by its ability to transfer sulfate from PAPS to heparan sulfate under the described conditions. |
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