| Cat# |
DIA-808 |
| Descriptions |
Protein O-Glucosyltransferase 1 (POGLUT1) catalyzes O-linked glucose modification of EGF repeat-containing proteins including Notch receptors, modulates protein folding and signal transduction efficiency, and plays critical roles in tissue development and homeostasis. |
| Applications |
Protein O-Glucosyltransferase 1 (POGLUT1) is suitable for EGF domain glycosylation detection kits and protein folding quality assay reagent development. |
| Enzyme Commission Number |
EC 2.4.2.63 |
| Enzyme Source |
Chinese Hamster Ovary cell line, CHO-derived human Protein O-Glucosyltransferase 1/POGLUT1 protein. |
| Reaction |
L-seryl-[EGF-like domain protein] + UDP-alpha-D-xylose = 3-O- (beta-D-xylosyl)-L-seryl-[EGF-like domain protein] + H+ + UDP |
| Activity Definition |
Measured by its ability to hydrolyze UDP-Glucose. |
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