RNase III is a double-strand-specific ribonuclease that cleaves double-stranded RNA into short duplex fragments with characteristic 3' overhangs, participates in RNA maturation and degradation processes, and is a core tool for RNA interference research and dsRNA processing.
Applications
RNase III is suitable for double-stranded RNA processing detection kits and RNA interference research reagent development.
Enzyme Commission Number
EC 3.1.26.3
Enzyme Source
This product is the RNase III recombinantly expressed in E. coli. This specific exonuclease is capable of cutting double-stranded RNA (dsRNA).
Activity Definition
1 active unit is defined as the amount of enzyme needed to degrade 1μg of dsRNA into siRNA in 20min at 37°C in a 50μL reaction system.