| Cat# |
DIA-870 |
| Descriptions |
ST6 Sialyltransferase 4 (ST6GALNAC4) mediates α-2,6 sialylation of ganglioside substrates to synthesize disialoganglioside structures, is highly expressed in neural tissues, and supports ganglioside biosynthesis and brain glycobiology research. |
| Applications |
ST6 Sialyltransferase 4 (ST6GALNAC4) serves as a raw material for disialoganglioside detection kits and neural glycan biosynthesis assay reagent development. |
| CAS No. |
24-3-71311 |
| Enzyme Commission Number |
EC 2.4.3.7 |
| Enzyme Source |
Trichoplusia ni, High Five (baculovirus)-derived human ST6GALNAC4 protein. |
| Reaction |
an alpha-Neu5Ac- (2->3)-beta-D-Gal- (1->3)-D-GlcNAc derivative + CMP-N-acetyl-beta-neuraminate = an alpha-Neu5Ac- (2->3)-beta-D-Gal- (1->3)-[alpha-Neu5Ac- (2->6)]-D-GlcNAc-R + CMP + H+ |
| Activity Definition |
Measured by its ability to transfer Neu5Ac from CMP-Neu5Ac to fetuin of fetal calf serum. |
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