| Cat# |
DIA-294 |
| Description |
The enzyme urate oxidase (UO), or uricase or factor-independent urate hydroxylase, absent in humans, catalyzes the oxidation of uric acid to 5-hydroxyisourate: Uric acid + O2 + H2O → 5-hydroxyisourate + H2O2 → allantoin + CO2 |
| Activity |
About 10U/mg |
| CAS No. |
9002-12-4 |
| Unit Definition |
One unit will convert 1μmol uric acid to oxidize per min at pH 8.5 and at 37°C. |
| Storage |
4°C, store at -20°C for long-term preservation. |
| Synonyms |
urate oxidase; uric acid oxidase; uricase; uricase; urate: oxygen oxidoreductase; EC 1.7.3.3; uricase II |
| Enzyme Commission Number |
EC 1.7.3.3 |
| Purity |
>90% (SDS-PAGE test) |
| Buffer |
20mM Tris, pH8.0 |
| Abbr |
UO, Recombinant |
| Alias |
UO |
| Applications |
Uricase cancatalyze the enzymatic oxidation of uric acid to allantoate rapidly, so it is used to detect the amount of uric acid in the serum and urine. |
| Appearance |
White powder, lyophilized |
| Molecular Weight |
About 45kDa (SDS-PAGE detection) |
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