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Alpha-N-Acetylglucosaminidase (NAGLU)

Cat# DIA-615
Descriptions Alpha-N-acetylglucosaminidase (NAGLU) is a lysosomal hydrolase specialized in hydrolyzing α-linked N-acetylglucosamine bonds in glycosaminoglycans, mediates intracellular heparan sulfate degradation, and is widely utilized in mucopolysaccharidosis mechanism research and enzyme activity detection assays.
Applications Alpha-N-acetylglucosaminidase (NAGLU) is applied in mucopolysaccharidosis type IIIB detection kit development and lysosomal enzyme activity assay reagent preparation.
CAS No. 32-1-5058
Enzyme Commission Number EC 3.2.1.50
Enzyme Source Chinese Hamster Ovary cell line, CHO-derived human alpha-N-acetylglucosaminidase/NAGLU protein.
Reaction Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.
Activity Definition Measured by its ability to hydrolyze 4-Nitrophenyl-N-acetyl-alpha -D-glucosaminide under the decribed conditions.
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