| Cat# |
DIA-615 |
| Descriptions |
Alpha-N-acetylglucosaminidase (NAGLU) is a lysosomal hydrolase specialized in hydrolyzing α-linked N-acetylglucosamine bonds in glycosaminoglycans, mediates intracellular heparan sulfate degradation, and is widely utilized in mucopolysaccharidosis mechanism research and enzyme activity detection assays. |
| Applications |
Alpha-N-acetylglucosaminidase (NAGLU) is applied in mucopolysaccharidosis type IIIB detection kit development and lysosomal enzyme activity assay reagent preparation. |
| CAS No. |
32-1-5058 |
| Enzyme Commission Number |
EC 3.2.1.50 |
| Enzyme Source |
Chinese Hamster Ovary cell line, CHO-derived human alpha-N-acetylglucosaminidase/NAGLU protein. |
| Reaction |
Hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. |
| Activity Definition |
Measured by its ability to hydrolyze 4-Nitrophenyl-N-acetyl-alpha -D-glucosaminide under the decribed conditions. |
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