| Cat# |
DIA-639 |
| Descriptions |
Beta-1, 3-N-Acetylglucosaminyltransferase 4 (B3GNT4) exhibits high substrate specificity for core 2 O-glycans, catalyzes β-1,3 N-acetylglucosamine addition to extend O-linked glycan chains, and is applied in mucin-type glycan synthesis and glycobiology studies. |
| Applications |
Beta-1, 3-N-Acetylglucosaminyltransferase 4 (B3GNT4) is suitable for core 2 O-glycan detection kit development and mucin glycosylation assay reagent preparation. |
| CAS No. |
24-1-1493 |
| Enzyme Commission Number |
EC 2.4.1.149 |
| Enzyme Source |
CHO-derived |
| Reaction |
A beta-D-galactosyl- (1->4)-N-acetyl-beta-D-glucosaminyl derivative + UDP-N-acetyl-alpha-D-glucosamine = an N-acetyl-beta-D-glucosaminyl- (1->3)-beta-D-galactosyl- (1->4)-N-acetyl-beta-D-glucosaminyl derivative + H+ + UDP |
| Activity Definition |
Measured by its ability to transfer N-acetylglucosamine from UDP-GlcNAc to beta -lactose. |
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