| Cat# | TRA-170 |
| Specification | 10μg(min) |
| Description | Full-length human BTK was expressed as an N-terminal DYKDDDDK-tagged, biotinylated protein 80 kDa using a baculovirus expression system. The protein was first purified with DYKDDDDK tag antibody agarose and then activated with ATP. The activated protein was subsequently purified by gel filtration. |
| Applications | For use as a critical control in BTK companion diagnostic assays for B-cell malignancy treatment selection. |
| Synonyms | BTK, AGMX1, AT, ATK, BPK, IGHD3, IMD1, PSCTK1, XLA |
| Source | Insect (sf21) |
| Molecular Weight | 80 kDa |
| Class | Non-Receptor Tyrosine Kinase |
| Group | TK |
| Family | Tec |
| Gene Name | BTK | Bruton tyrosine kinase |
| Sequence | 2-659 (end) |
| Accession Number | NP_000052.1 |
| Tag | BTN-Tag |
| Tag Location | N-terminal DYKDDDDK |
| Storage Buffer | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35,1 mM DTT, 10% glycerol, pH 7.5 |
| Storage | Store at -80°C. Avoid repeating freeze-thaws. |
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