| Cat# | TRA-323 |
| Specification | 10μg(min) |
| Description | The cytoplasmic domain of human KIT was produced as an N-terminal DYKDDDDK-tagged, biotinylated protein 53 kDa using a baculovirus expression system. Following purification with DYKDDDDK tag antibody agarose and activation with ATP, the activated protein was isolated by gel filtration. |
| Applications | For use as a positive control in KIT mutation detection assays for GIST and melanoma companion diagnostics. |
| Synonyms | KIT, C-Kit, CD117, MASTC, PBT, SCFR |
| Source | Insect (sf21) |
| Molecular Weight | 53 kDa |
| Class | Receptor Tyrosine Kinase |
| Group | TK |
| Family | PDGFR |
| Gene Name | KIT | KIT proto-oncogene, receptor tyrosine kinase |
| Sequence | 544-976 (end) |
| Accession Number | NP_000213 |
| Tag | BTN-Tag |
| Tag Location | N-terminal DYKDDDDK |
| Storage Buffer | 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35,1 mM DTT, 10% glycerol, pH 7.5 |
| Storage | Store at -80°C. Avoid repeating freeze-thaws. |
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